LIFR CHO
CBP74600
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| I. Background | |
| LIFR基因编码白血病抑制因子受体（Leukemia Inhibitory Factor Receptor），是一种属于I型细胞因子受体家族的跨膜蛋白。它必须与辅助亚基gp130形成异源二聚体复合物，才能高亲和力地结合LIF、抑瘤素M（OSM）、睫状神经营养因子（CNTF）等多种配体，并激活JAK/STAT、PI3K/AKT等下游信号通路，调控细胞的增殖、分化和存活。 | |
| II. Description | |
| LIFR CHO细胞，在 CHO-K1 细胞的基础上，稳定表达 LIFR 。 | |
| III. Introduction | |
| Expressed gene: | LIFR |
| Host Cell: | CHO |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant LIFR CHO constitutively expressing LIFR. |
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